Cutting Edge Health: Preventing Cognitive Decline

Dr. Richard Restak - Paying Attention Is the Key to Preserving Memory - Cutting Edge Health Audio Podcast

Dr. Richard Restak concurs with the 18th century British writer, Samuel Johnson, who once said, “The true art of memory is the art of attention.”A neurologist and neuropsychologist and expert on the human brain, Dr. Restak believes that all methods of nourishing and protecting one’s memory entail the ability to focus attention. His favorite technique is turning words into visual images to establish what he calls a “memory path.”“Seeing something and converting the word or a sense into a picture, into a mental drawing, is the key to setting up memory,” he explains.Dr. Restak also advocates other paths for protecting one’s memory - cooking (which can require organization and memorization of recipes), the use of technology (to support memory, not replace it), getting adequate sleep, playing games, avoiding fast food and trending toward vegetarianism, and exercising. Guest Bio:Dr. Richard Restak is a noted neurologist and neuropsychiatrist who has written extensively on the subject of the human brain.He is the author of 20 books, all on aspects of the brain, two of which were New York Times Best Sellers - The Brain (1984) and The Mind (1988). Both those books were turned into television series by the Public Broadcasting System.His most recent book, The Complete Guide to Memory: The Science of Strengthening Your Mind, published in 2021, is a cornucopia of information on memory and offers numerous suggestions for how individuals can enhance their memory and protect it from deteriorating.Dr. Restak earned degrees from Gettysburg College and Georgetown University School of Medicine. He completed his internship at St. Vincent’s Hospital in New York City and residencies at Georgetown University Hospital and George Washington University Hospital. Now 80, he still has a private practice in  neurology and neuropsychology and is a clinical professor of neurology at George Washington Hospital University School of Medicine and Health.Often appearing as a guest on television and radio shows, Dr. Restak has written articles for numerous newspapers and contributed entries on neuroscience and the brain to the Encyclopedia Brittanica and the Encyclopedia of Neuroscience.
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Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan, Maria, Louis, and Nicole on the Cutting Edge Health team!

Dr. Pam Maher - CBN, a Non-Psychoactive Cannabis Chemical, May Protect Cognitive Functioning - Cutting Edge Health Audio Podcast

The Salk Institute’s Cellular Neurobiology Laboratory, which Pamela Maher, PhD heads, has been studying CBN. It is a chemical found in marijuana and findings show how it can protect nerve cells in the brain from oxidative damage, a major pathway to cell death. Their research also suggests that CBN works to protect the brain’s mitochondria. Mitochondria is called the powerhouse of a cell. 
Pair these two findings and the neuroprotective benefits CBN produces might be helpful in preventing diseases like Alzheimer’s and Parkinson’s, Maher says. However, human clinical trials are still years away. The lab’s research thus far involves only mice.
CBN is molecularly similar to THC, but is not psychoactive. Because it won’t get one high, it is legal in every state. CBN is already produced commercially, sometimes in pill form, gummies or tinctures. Evidence suggests it is safe in animals and humans. 
Dr. Pamela Maher, a neuroscientist, is a research professor at the Salk Institute and the head of Salk’s Cellular Neurobiology Laboratory. A senior staff scientist at Salk since 2004, she has concentrated her research on screening for compounds that can halt the progress of neurodegenerative brain disorders, including Alzheimer’s disease.
Dr. Maher's website: https://www.salk.edu/scientist/pamela-maher/
Maher earned her undergraduate degree in Biochemistry from McGill University in Montreal, a PhD in Biochemistry from the University of British Columbia in Vancouver, and a Postdoc in Cell Biology from the University of California, San Diego.
In 1979 she was granted a Killam Predoctoral Fellowship, in 1980 an Anna Fuller Postdoctoral Fellowship, and in 1982 an NIH Postdoctoral Fellowship.
Dr. Maher has been the recipient of several major awards, including the Michael J. Fox Foundation Award for Novel Approaches to Drug Discovery for Parkinson’s Disease in 2007 and the Edward N. And Della L. Thome Memorial Foundation Award in Alzheimer’s Disease Drug Discovery in 2015.
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Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
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Dr. Gary Small - How to Live to Prevent Alzheimer’s - Cutting Edge Health Audio Podcast

Dr. Gary Small, former Director of UCLA’s Longevity Center and currently Behavioral Health Physician-in-Chief at Hackensack Meridian Health, believes lifestyle choices can eclipse genetics to stymie Alzheimer’s disease.
Genetics influences cognitive health, Dr. Small acknowledges, but physical and mental exercise, managing stress and eating well can counteract the disease as individuals age. Even if people are at genetic risk, their behavior and length of life will determine if they get the disease, he says.
Dr. Small is sanguine about the future, as studies show that lifestyle changes do lower the rate of contracting Alzheimer’s. The high hurdle to cross, he concedes, is motivating people — in a pill-dependent society — to live healthier lives.
Nationally renowned psychiatrist Gary W. Small, M.D., joined Hackensack Meridian Health as its Behavioral Health Physician-in-Chief on November 1, 2020. In this newly created position, Dr. Small oversees all professional and administrative activities within the behavioral health care transformation service at Hackensack Meridian Health, as well as serving as Chair of Psychiatry at Hackensack University Medical Center. 
Prior to joining Hackensack Meridian Health, Dr. Small was a professor of psychiatry and biobehavioral sciences, Parlow-Solomon professor on aging at the David Geffen School of Medicine at UCLA, director of the Division of Geriatric Psychiatry at the Semel Institute for Neuroscience & Human Behavior and director of the UCLA Longevity Center. 
Dr. Small is known nationally and internationally for his public work in promoting the practice of psychiatry and innovative research on brain health and aging. Dr. Small has authored more than 500 scientific publications as well as the international best-seller, The Memory Bible. Small’s research has been featured in The New York Times, Wall Street Journal, London Times, Washington Post, Time Magazine, and Newsweek.
Dr. Small's media links- Website: htthttp://drgarysmall.com/
Facebook: https://www.facebook.com/DrGarySmallFanPage/
Twitter:  @drgarysmall
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Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan, Maria, Louis and Nicole on the Cutting Edge Health team!

Sara Mednick PhD - Deep Sleep Amount In Your 40’s & 50’s Predicts Dementia Decades Later - Cutting Edge Health Audio Podcast

A good way to keep one’s cognitive faculties strong is to go to bed at a decent hour, according to Dr. Sara Mednick, director of the Sleep and Cognition Lab at the University of California, Irvine.
Her research shows the amount of deep sleep we get in mid-life is critical for preventing dementia as we age.  It’s so important that Dr. Mednick recommends getting to bed at 9pm since deep sleep happens at the beginning of the night and you want to get as much of it as possible. 
A phase of sleep she calls “downstate” is important to the rhythm of life because it allows people to restore energy for their waking hours.
If toxic proteins accumulated in the brain during daytime are not flushed out at night, they can build into “plaques and tangles” that become part of dementia.
Healthy long-term sleep patterns, Dr. Mednick says, can prevent “memory pathologies.” 
Professor Sara Mednick, PhD is a cognitive neuroscientist at the University of California, Irvine and author of The Power of the Downstate. She is passionate about understanding how the brain works through her research into sleep and the autonomic nervous system. Dr. Mednick’s seven-bedroom sleep lab works literally around-the-clock to discover methods for boosting cognition by napping, stimulating the brain with electricity, sound and light, and pharmacology. Her lab also investigates how the menstrual cycle and aging affect the brain. Her science has been continuously federally funded (National Institute of Health, National Science Foundation, Department of Defense Office of Naval Research, DARPA).
Dr. Mednick's media links- Website: http://www.saramednick.com/
Instagram: @sara_mednick_downstate
Twitter: @Sara_Mednick
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Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan, Maria, Louis and Nicole on the Cutting Edge Health team!

Dr Enid Taylor - Fecal MicrobiotaTransplants (FMT) Support the Gut-Brain Connection. Cutting Edge Health Audio Podcast

Fecal microbiota transplants (FMT), an emerging procedure treating large intestinal infections and bowel disorders, may help combat Alzheimer’s and Parkinson’s diseases. The transplants have not been officially approved in the U.S. but have proven effective, without adverse consequences, at curing patients of bacterial infections known as C. difficile. “It’s actually making people well,” said Dr. Enid Tayler, director of the Taymount Clinic in Hertfordshire, U.K., which specializes in FMT. The procedure transplants donors’ healthy fecal bacteria into individuals suffering from gut infections. Clinical studies have been launched evaluating FMT’s seemingly positive impact on Alzheimer’s and Parkinson’s.
Guest Media links-
Website: https://taymount.com/
Facebook: https://www.facebook.com/TaymountClinic
YouTube channel: https://www.youtube.com/channel/UCbb7mX_nxE1kGPHsbDPt4TQ
Twitter: https://twitter.com/TaymountClinic
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Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed. Special thanks to Alan, Maria, Louis and Nicole on the Cutting Edge Health team!

Dr Lisa Broyles ’Brain Boosting Mushrooms’ Cutting Edge Health Audio Podcast

Mushrooms have long been thought to possess medicinal powers. Experts like Dr. Lisa Broyles suggest they even can nourish cognitive health. Many foraged mushrooms contain properties that can boost cognitive powers or curtail brain degeneration, according to Dr. Broyles, a family medicine specialist.  
Lion’s mane, she says, helps the brain and neurons regenerate after they are damaged and slows the production of amyloid, a key protein associated with Alzheimer’s disease. Chaga and chicken in the woods improve the body’s handling of insulin — a recipe for keeping the brain healthy. Psilocybin, or “magic mushrooms,” improve memory and cognitive abilities, explains Dr. Broyles.
Mushrooms are eaten directly or turned into tinctures and consumed in beverages like tea. Many such therapeutic tinctures are sold commercially, she says.
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Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan, Maria, Louis and Nicole on the Cutting Edge Health team!

Dr. Dayan Goodenowe ’How to Overcome the Alzheimer’s Gene’ Cutting Edge Health Audio Podcast

Dayan Goodenowe, PhD, founder, president and CEO of Prodrome Sciences, which promotes disease prevention through detection and treatment, believes supplements and behavior modification can play a role in combating dementia.
His target is the little-known lipid, plasmalogen, which he cited in his book, Breaking Alzheimer’s, as a cause of Alzheimer’s.
Like many molecules, plasmalogens that are typically healthy in youth and middle-age deteriorate during old age. That can lead to the onset of Alzheimer’s, according to Dr. Goodenowe, because of the lack of plasmalogen in membranes in the neurological system.
When membranes become deficient in plasmalogens, as happens during aging, they can create an impairment of synaptic function, and that, according to Dr. Goodenowe, reduces neurological function typically associated with dementia.
He compares the neurological system to the wires in a house’s lighting network. Lights are turned on by a switch, whereas neurons communicate with each other through biochemical molecules. And plasmalogens serve as biological fuses. They are a critical building block of the membranes that protect and compartmentalize the various functions of the body, including the neurological workings of the brain.
Supplements provide a way to boost the number and efficiency of plasmalogens and warding off dementia in the elderly, Dr. Goodenowe says, by maintaining a proper cell level so that the lipids produce their own plasmalogens. Another strategy is to practice intermittent fasting, he explains, because it can help control fat metabolism. He also recommends a balanced diet and the consumption of animal fat to build plasmalogen and stave off dementia. Other bodily processes that can spur dementia, such as brain shrinkage, amyloid plagues, and neurofibrillary tangles, also can be measured and controlled, according to Dr. Goodenowe. In fact, brain shrinkage is impacted by plasmalogens, Dr. Goodenowe asserts. When the brain shrinks, it loses lipids, and one critical lipid it loses is plasmalogen.
Dr. Goodenowe says that individuals with high plasmalogens live and function longer — by about 30 years — than those with low plasmalogens. In fact, he contends, plasmalogens are a better indicator of longevity than age.
People can overcome the potential impact of their genes, Dr. Goodenowe maintains — even when someone has APOE4, the gene scientists say carries the greatest risk for dementia. One of the plasmalogens’ many functions is to regulate cholesterol, and as humans age, and their plasmalogens become deficient, they are less able to export cholesterol, a condition that is more acute in those with the APOE4 gene. When an APOE4 carrier ages, it can lead to higher cholesterol in the membranes, which has an impact on the amyloid pathway. Amyloid plaque can form in the brain, which can lead to synapse dysfunction and dementia.
People can measure their plasmalogens through blood tests. Dr. Goodenowe’s company, Prodrome sciences, does offer such testing. You can learn more at Prodrome.com. Dr. Goodenowe says the key is to check plasmalogens in relation to other molecules in your body. You want your plasmalogen level to be higher than the non-plasmalogen level, he points out, because it helps maintain the body’s cells.
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Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan, Maria, Louis and Nicole on my team!

Dr. Gonzalez-Lima ’Methylene Blue: Another Road To Brain Health?’ Cutting Edge Health Audio Podcast

Francisco Gonzalez-Lima, PhD is one of the world’s leading neuroscientists and his research offers hope to millions of potential Alzheimer’s patients.  
He’s spent decades researching what goes wrong that can lead to Alzheimer’s.  It’s not the amyloid hypothesis which he calls “the world’s biggest bio-medical research mistake of his lifetime.”  He’s found in 9 out of 10 cases of Alzheimer’s there is no inheritance or familial component.  Instead, it’s an accumulation of lifestyle factors that lead to the disease.  He discusses the danger of mid-life obesity, blood pressure, the thickness of the carotid artery wall, exercise, and diet. 
Dr. Gonzalez-Lima’s research finds that a very low amount of methylene blue (of pharmaceutical USP purity) in the body can promote brain oxygen consumption by an enzyme called cytochrome oxidase to power the mitochondria. In his analysis of many Alzheimer’s brains he found an inhibition of cytochrome oxidase in all of them. Methylene blue supplementation compensates for that problem.
Safety warning:  Don't take methylene blue if you're on an antidepressant, especially SSRIs and SNRIs, as high levels of serotonin can build up in the brain causing toxicity.
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Please note that The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan, Maria and Nicole on my team.

Dr. Heather Sandison ’Alzheimer’s is Optional’ Cutting Edge Health Audio Podcast

Dr. Heather Sandison is founder of Marama, a first-in-the-world senior living facility with a goal for residents to return to independent living. In this episode she explains there are so many things we can do to improve our cognitive health starting today regardless of where you might be on the spectrum of risk or decline. Please know, she says, that there’s hope for anyone suffering with dementia, and this is an absolutely preventable disease.”
Heather Sandison, ND specializes in neurocognitive medicine and neuro hacking. She is the founder and medical director of Solcere and the founder of Marama, a senior living facility with a goal for residents to return to independent living.
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Please note that The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan and Nicole on my team.

Dr. Lisa Broyles ”Pegan Diet” on Cutting Edge Health Audio Podcast

Keeping your brain healthy means feeding it the right food. In this episode, Jane Rogers and Lisa Broyles discuss how to adopt the diet that works best for you as an individual. 
Dr. Lisa Broyles, MD, is trained in the Bredesen Protocol, a personalized program to prevent and reverse cognitive decline. For the past several years, she served patients at urgent care and occupational medicine centers in South Carolina and Tennessee. Prior to this, she was medical director for the East Tennessee Spine and Nerve Center in Chattanooga and the Johnson City Tennessee Downtown Clinic. Dr. Broyles graduated from Brody school of medicine at East Carolina University in Greenville North Carolina and obtained her functional medicine certification from Functional Medicine university in Greer South Carolina.
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Dr. Broyles website: http://way2healthmd.com/
Please note that The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan and Nicole on my team.