Cutting Edge Health: Preventing Cognitive Decline

Dr. Manju Sabramanian - The Eyes Have It: Potential For Early Alzheimer’s Diagnosis

Research at Boston University has led to the discovery of a non-invasive method to diagnose Alzheimer's.  This opens the door in the coming years to possibly detecting the disease in its early stages, decades before real symptoms appear. 
Manju Subramanian, MD and her team found that proteins in eye fluids are providing this window to the brain. These eye fluids are confirming pathological brain conditions like dementia in the Alzheimer's form. Until now, MRIs and lumbar punctures were the tools to aid the clinical diagnosis of Alzheimer's, but that has meant late detection when the disease is already in place. Alzheimer's is not actually confirmed until after death and a post-mortem examination of the brain is done. 
"We know that patients with eye disease tend to be an at-risk population for dementia. Patients with macular degeneration, glaucoma and diabetic retinopathy, those are the three big ones," says Subramanian.
The potential of an eye fluid exam at an optometrist's office is ideal as it's non-invasive and not expensive.  But, it is still several years out before potentially becoming commonplace.  More research is needed. Still to be determined in future research is just how early eye fluid proteins become abnormal when dementia is developing.  
"As they say, the eye is the window to the soul.  It is also very much the window to the brain," says Subramanian.
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Manju Subramanian is an Associate Professor in Ophthalmology and Vice-Chairman of Faculty Affairs. She is an ophthalmic surgeon specializing in Vitreoretinal Disease and Surgery, and is in academic practice at Boston Medical Center. She also sees patients at the Dedham Ophthalmic Consultants. Her primary areas of clinical interest include medical and surgical management of diabetic retinopathy, age-related macular degeneration, retinal detachments, hereditary retinal diseases, ocular inflammation, and ocular trauma. Dr. Subramanian graduated from the University of Missouri School of Medicine and completed her residency at the University of Kansas Medical Center in 2002. She completed a fellowship in Vitreoretinal Disease and Surgery at Tufts University School of Medicine and Ophthalmic Consultants of Boston in 2004.
Dr. Subramanian’s research interests include the study of eye-based biomarkers for Alzheimer’s Disease (AD), age-related macular degeneration, diabetic retinopathy, and the role of anesthesia in eye surgery. She was Principal Investigator for the first head to head clinical trial comparing the use of bevacizumab and ranibizumab in the treatment of age-related macular degeneration, and she is currently the Principal Investigator for a study assessing the role of oral sedation in eye surgery. She is also a recent recipient of an R03 Grant Award by the National Institutes of Aging as the Principal Investigator of a study looking at protein biomarkers for AD in the eye.
In her role as Vice-Chairman of Faculty Affairs at Boston University Eye Associates, she works in a supportive role in the professional and career development and engagement of the clinical faculty. Prior to 2017, she served as the Vice-Chairman of Clinical Services for 8 years. She serves on several institutional committees, including the Women’s Leadership Advisory Council, the Boston University Medical Group (BUMG) Research Committee, the BU School of Medicine Promotion Criteria Working Group, and also serves as Chair of the BUMG Professional Development Committee. She additionally serves on national committees, such as the International Meetings Committee for the American Academy of Ophthalmology (AAO), the Diversity Initiatives Committee for the Association for Research in Vision and Ophthalmology (ARVO), and a Special Emphasis Panel for a Study Section with the National Institutes of Health.
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Cutting Edge Health podcast website: https://cuttingedgehealth.com/
Cutting Edge Health Social and YouTube:YouTube channel: youtube.com/@cuttingedgehealthpodcastInstagram - https://instagram.com/cuttingedgehealthpodcastFacebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756
Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan, Maria, Louis, and Nicole on the Cutting Edge Health team!

Dr. Kat Toups - The Science of Reversing Dementia

Dementia can be prevented, and Kat Toups, MD knows this firsthand.  Dr. Toups is a San Francisco Bay Area psychiatrist, but she is also an accomplished researcher who led investigations in 20 extensive clinical trials focused on Alzheimer's and MCI (Mild Cognitive Impairment). While working in this area, she developed dementia herself, and by using functional medicine, she reversed her own decline. 
Dr. Toups thrives on helping people. She partnered with Dale Bredesen, MD on a clinical trial using functional medicine, often called precision medicine, where 84% of the study patients with MCI and early dementia had improvements as shown on their MRI brain scans and other cognitive assessments. The study’s results were published in the Journal of Alzheimer's Disease in August 2022:  Precision Medicine Approach to Alzheimer’s Disease: Successful Pilot Project.
Following this success, Dr. Toups has now launched a much larger clinical trial in six cities around the United States. Participants must live within an hour’s drive of one of these locations:
Walnut Creek (San Francisco East Bay), CA
San Rafael (San Francisco/Marin County), CA
Sacramento (El Dorado Hills), CA
Miami (Hollywood), Florida
Nashville (Brentwood), Tennessee
Cleveland (Rocky River), Ohio
For more information: www.dementiareversaltrial.com
Dr. Toups says dementia happens for multiple reasons. It doesn’t just come out of nowhere, but likely has been slowly building for more than a decade.  Dr. Toups says it’s critical to search for contributing factors at the earliest opportunity if you want success in stopping or reversing disease progression. In this interview, she elaborates on the importance of partnering with a functional medicine doctor to do this work.  Some of the core contributors to cognitive problems might be inflammatory load in the body, heart health, hormone levels, exercise, stress, sleep, toxins, and infections amongst many other factors.
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Kat Toups, M.D., DFAPA, IFMCP is a functional medicine psychiatrist at Bay Area Wellness in Walnut Creek, CA. Dr. Toups is a distinguished fellow of the American Psychiatric Association (the highest honor bestowed by the APA), board certified by the American Board of Psychiatry and Neurology, and previously boarded in geriatric psychiatry.
Dr. Toups is a former assistant professor of psychiatry at UC Davis, where she was the inpatient residency training director, and later the owner/medical director of Bay Area Research Institute, a clinical trials research center in Lafayette, CA. After serving as the principal investigator on over 100 clinical trials for 12 years, including 20 failed trials for Alzheimer's drugs, she realized that the elusive cure for brain and psychiatric illness was not going to be found in a pill.
She embarked on an intensive course of study (initially sparked by a quest to heal her own serious autoimmune disease) to learn functional and nutritional medicine and completed her training for the Institute for Functional Medicine Certification in October 2013.
Dr. Toups practices functional medicine psychiatry, which seeks to discover the underlying causes of inflammation (like diet/nutrition, lifestyle, genetics including MTHF/Methylation/Sulfation/Detoxigenomic genetic polymorphisms, GI health including food allergies and dysbiosis, toxin exposure, chronic infections, and biochemical abnormalities) that can all be contributors to problems with psychiatric symptoms and/or cognition difficulties. Detection and correction of these problems can result in the resolution of the psychiatric symptoms, rather than just providing a band-aid by only prescribing psychiatric medications without addressing the underlying causes of the problem.
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Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan, Maria, Louis, and Nicole on the Cutting Edge Health team!

Dr. Eric Larson - What’s Aging Seattlites?

Dr. Eric Larson is a leading expert on aging and dementia and one of the creators of a massive living lab studying the brains of 5000 Seattle residents as they age over decades. The research is called the Adult Changes in Thought (ACT) Study. Dr. Larson is optimistic when it comes to preventing the devastating disease, but not because miracle medicines might be on the horizon. Instead, he believes Alzheimer’s and other types of dementia are directly impacted by the lifestyle choices individuals make. He’s finding people are increasingly paying attention to those lifestyle issues and doing the right thing for their health.
In fact, as an example, he says, the closest thing to a magic pill for reducing the risk of dementia is probably exercise.  But that is just one of the 12 modifiable risk factors to prevent the disease. Larson speaks to the dozen modifiable risk factors that were presented in a 2020 report of the Lancet Commission and they include:  less education, hypertension, hearing impairment (between the ages 45-65 hearing loss is the biggest modifiable risk factor), smoking, obesity, depression, physical inactivity, diabetes (type 2 leads to a two-fold increased risk of developing AD), low social contact, excessive alcohol consumption, traumatic brain injury, and air pollution.
“There is no inevitability about this condition,” he says of the loss of cognitive functioning. “I was reading the numbers. There's a 1/3 drop from 2000 to 2016 in the rates of dementia in North America and Europe. We have reached a point where people are better educated, socio and economic indicators have improved. We're not doing the same stuff our parents were doing as far as health. We realize we need to exercise, and not smoke, and not drink a bunch of alcohol.”
On the other hand, Dr. Larson worries that dementia is increasing in less-advanced, industrializing societies that adopt some of the unhealthier aspects of the Western lifestyle. 
Some of the choices that people can make to diminish the risk of Alzheimer’s, besides engaging in physical exercise, are controlling weight and blood pressure; treating or protecting against diabetes; quitting smoking; moderating alcohol consumption; and addressing hearing loss and perhaps even vision impairment. 
"A lot of the things that reduce the risk of dementia and Alzheimer's disease are the things that improve health and well-being in older people,” points out Dr. Larson, who recently retired. But individuals should not wait until they approach old age to adapt to a healthy lifestyle. The earlier they begin, the more likely they are to diminish the chances of losing cognitive function.
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Dr. Eric B. Larson was executive director of Kaiser Permanente Washington Health Research Institute (KPWHRI) and vice president for research and healthcare innovation at Kaiser Foundation Health Plan of Washington. A general internist, he was a professor of medicine at the University of Washington in Seattle. He recently retired from full-time work, but continues to be active in the field of geriatrics and works part time at the University of Washington’s Department of Medicine as a professor of medicine.
Dr. Larson began at the University of Washington as a fellow in 1975 after graduating from Harvard Medical School. He served as medical director at the University of Washington Medical Center and was associate dean for clinical affairs from 1989 until 2002.  Dr. Larson joined Group Health (now Kaiser Permanente) in 2002 to lead the Center for Health Studies. His research on aging includes a longstanding collaboration between Kaiser Permanente Washington and the University of Washington called the Adult Changes in Thought (ACT) Study. With colleagues from University of Washington and Group Health, he received a demonstration grant from the National Institutes of Health to establish a model Alzheimer’s disease registry in 1986.  This morphed into the landmark Adult Changes in Thought study with the establishment of the initial cohort of 2581 randomly selected volunteers who joined the study 1994-96. The cohort has doubled since then and is one of the longest continuous studies on aging and dementia in the world.
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Cutting Edge Health podcast website: https://cuttingedgehealth.com/
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Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan, Maria, Louis, and Nicole on the Cutting Edge Health team!

Dr. Lisa Broyles - Love Up Your Liver

Keeping your liver clean is yet another way to boost your cognitive longevity and enhance the likelihood that your brain stays sharp as long as possible. Though many people pay little attention to the liver and have scant knowledge of what it does, this vital organ performs many critical roles in enabling the body to continue functioning. Most significantly, it rids the bloodstream of harmful toxins.  
“Your liver is vitally important,” explains Dr. Lisa Broyles. “It removes toxins and chemicals that are dangerous for us from our blood and gets rid of them.”
Dr. Broyles, a certified functional medicine doctor who is specially trained in preventing and reversing cognitive decline, says that people should pay attention to the liver and take steps to detoxify the organ if it is struggling to perform its many functions. Among those functions, besides detoxifying the blood stream, are producing and regulating the level of cholesterol, regulating sex hormones, storing sugar when the body needs it, tending to the body’s immune health, and guarding against blood clotting.  
When the liver is having difficulty in its effort to remove bodily toxins, it can lead to such problems as migraine headaches, autoimmune disease, cancer, lupus, and arthritis.
The liver must be clean, Dr. Broyles says, if it is to effectively do its job.
“I do think that every six months, ideally, everyone should do a liver and gallbladder flush, and followed by some colon hydrotherapy, both before and after,” she recommends. Dr. Broyles says that a number of companies offer liver cleansing approaches and kits.
She talks about three phases of liver detoxification - oxidation, conjugation (making toxins more water soluble so they excrete into the intestines and leave the body), and transportation where toxins are broken down (to assure a healthy gallbladder).  
The food you eat and the medicines and vitamins you take can all enhance — or in some cases hinder — the the way the three phases clean the liver of its toxins. For instance, Tylenol can shut down the process of liver conjugation, according to Dr. Broyles. She points out that genetic make-up also plays a role in liver detoxification; each person is different and testing can help determine the right steps to take in cleaning the liver.   
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Dr. Lisa Broyles, MD, is trained in the Bredesen Protocol, a personalized program to prevent and reverse cognitive decline. It is estimated that nearly 50 million currently living Americans will die of Alzheimer’s disease if effective prevention and reversal are not implemented–almost 100 times more than have died of COVID-19. Mainstream medicine would have you believe that it can’t be prevented, is untreatable, and progressive, with most patients not surviving beyond three to eleven years post-diagnosis. But we are learning that the disease is a pathology of multiple causes that is preventable and even reversible in the early stages through the kind of holistic and individualized approach prescribed by the Bredesen Protocol. A certified functional medicine doctor with an interest in holistic/integrative medicine, Dr. Broyles is transforming medical care in rural North Carolina. Addressing the underlying causes of disease rather than simply treating symptoms, Dr. Broyles uses a systems-oriented, holistic approach that engages both patient and practitioner in a therapeutic partnership. The result has been a palpable rise in health IQ and wellness in the community she serves. “People are hungry for this kind of patient/physician collaborative care. They want to take charge of their well-being. They want to feel empowered. Too often, though, the insurance system in America limits choices for physicians and patients alike. Functional medicine represents a fundamental paradigm shift from symptom suppression to an integrative body/mind approach to optimal health,” said Dr. Broyles. Hoping to help more people than her limited practice can accommodate, Dr. Broyles is reaching out to her community through the Cutting-Edge Health podcast and other platforms.  Having graduated from the Brody School of Medicine at East Carolina University and completed her three-year residency at the University of Tennessee in Knoxville, Dr. Broyles is currently a family practitioner in Saluda, North Carolina. For the past several years, she served patients at urgent care and occupational medicine centers in South Carolina and Tennessee. Prior to this, she was medical director for the East Tennessee Spine and Nerve Center in Chattanooga and the Johnson City Tennessee Downtown Clinic. Dr. Broyles graduated from Brody school of medicine at East Carolina University in Greenville North Carolina and obtained her functional medicine certification from Functional Medicine university in Greer South Carolina. *****
Cutting Edge Health podcast website: https://cuttingedgehealth.com/
Cutting Edge Health Social and YouTube:YouTube channel: youtube.com/@cuttingedgehealthpodcast
Instagram - https://instagram.com/cuttingedgehealthpodcastFacebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756
Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan, Maria, Louis, and Nicole on the Cutting Edge Health team!

Dr Jeffery Galvin -Secrets to Getting Young Again

If you aspire to live a long life, don’t wait until you are 60 to pursue it, advises Dr. Jeffrey Galvin, director of the Vitality Medical Wellness Institute  North Carolina. The earlier you begin living a lifestyle aimed at longevity, the more likely you are to reach your 90’s and beyond in health, he suggests. 
“How do we build vibrant, healthy 90-year-olds?” he asks. “We start with 30 and 40-year-olds, maybe 50-year-olds.”
Galvin anticipates technologies, just over the horizon, that will radically extend human life. And current research (on mice and other animals) seeks to remove a body’s degraded cells and replace them with younger ones as a vehicle toward longevity.
But Dr. Galvin’s practice, the Vitality Medical Wellness Institute in Charlotte, NC, is not just trying to enable patients to live longer but also to enable them to be healthier as they age. “The idea is you want to stay healthy and performing really well for a long time,” he says.
Dr. Galvin wants to optimize peoples’ performance as long as possible and lessen the decline that often precedes death. He thinks it better to live to 90, and have just two years of decline rather than endure decades of decline even while living longer.
Another reason to strive for a healthy life sooner rather than later, he says, is that the life-prolonging technologies to become available in a few years won’t be accessible to the unhealthy. But,“If you're 75 and you're in top shape, then you're going to absolutely be eligible for those therapies."
He laments that most doctors treat disease and symptoms to manage decline but don’t show interest in patients’ overall health. He doesn’t blame the doctors themselves — “The system is not set up for you to be healthy,” he asserts.
Major causes of death — strokes and heart attacks, cancer, Alzheimer’s — must be minimized in advance. That entails evaluating family history and personal risk factors, testing for disease markers and planning how to uproot these potential seeds of death. “It really is important to do this testing and look at people's baseline health,” Dr. Galvin says. "We reverse chronic disease, because you can't really optimize until you get rid of all the underlying problems.”
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Jeffrey Galvin is the medical director and founder of Vitality Medical Wellness Institute. He is board-certified in emergency medicine and obesity medicine.  He served as a major in the United States Air Force, specializing in trauma and emergency care.  After completing his military service, he settled in Concord, NC, with his wife and three children. With over 25 years’ experience working in some of the busiest emergency departments in the country, he has cared for over 50,000 emergency and trauma patients.
Dr. Galvin has extensive training and experience in functional medicine, hormonal optimization, fitness, nutrition, genomics and epigenetics, and brain peak performance.  He is an expert biohacker experienced in nootropic use, peptide therapies, heart rate variability training, and sleep hacking.  His goal is maximizing human performance, reversing chronic disease and optimizing overall health.
Dr. Galvin founded Vitality Medical Wellness Institute in 2010.  It was born out of frustration with modern medicine’s focus on treating symptoms of illness, not the underlying causes. The Institute seeks to change the paradigm by which the medical establishment trains doctors to treat chronic medical problems with medication while ignoring the root origins of disease.  Dr. Galvin believes that by focusing on nutrition, fitness, hormonal optimization, and permanent lifestyle changes, health can be optimized. By utilizing this approach his patients are able to reverse chronic medical conditions, lose weight and maximize performance. At the same time risk of future disease is minimized.
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Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan, Maria, Louis, and Nicole on the Cutting Edge Health team!
 

Dr. Lisa Broyles - Bioidentical HRT Makes for a Bright Mind

Most women should consider bioidentical hormone replacement therapy at menopause to increase estrogen production and enhance their health and cognitive functions, according to Dr. Lisa Broyles, a functional medicine doctor.
“We can prove that it does improve cognition and lessens the risk of you developing Alzheimer's in the future,” she says.
Even prior to menopause, those women who experience symptoms like anxiety, forgetfulness and sleep difficulty should contemplate the hormone therapy, Dr. Broyles suggests.
“Studies show the sooner that you start it, the better you're going to do as far as your cognition,” she says. “Women that start it right away when they go through menopause and stay on hormone therapy for those first 10 years, between ages 50 to 60, consistently have less risk of developing Alzheimer's dementia than those that aren't on it at all, or that start it after that 10-year period.
She strongly cautions, however, that women focus on bioidentical hormone replacement therapy, or that which is similar to human-grade progesterone. Research two decades ago by the Women’s Health Initiative found that some estrogen replacements — particularly those that contained the synthetic progesterone, medroxyprogesterone — diminished cognition and potentially could lead to heart attacks or breast cancer. Dr. Broyles also recommends avoiding oral replacement therapy and advises that all women first consult doctors since individual risk factors must be taken into account prior to initiating the bioidentical hormone replacement therapy.
Sections of the brain first impacted by Alzheimer’s — including the hypothalamus, the pituitary gland and the forebrain — all have estrogen receptors, Dr. Broyles points out. Estrogen makes blood vessels more pliable and increases the strength of synaptic signals in the brain that allow for neurons to communicate with one another and reproduce more freely.
Progesterone to Estrogen Ratio Calculator 10:100Personally, I’ve read the ideal is a ratio in this online calculator of 10. https://www.omnicalculator.com/health/pg-e2-ratio
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Dr. Lisa Broyles, MD, is trained in the Bredesen Protocol, a personalized program to prevent and reverse cognitive decline. It is estimated that nearly 50 million currently living Americans will die of Alzheimer’s disease if effective prevention and reversal are not implemented–almost 100 times more than have died of COVID-19. Mainstream medicine would have you believe that it can’t be prevented, is untreatable, and progressive, with most patients not surviving beyond three to eleven years post-diagnosis.
But we are learning that the disease is a pathology of multiple causes that is preventable and even reversible in the early stages through the kind of holistic and individualized approach prescribed by the Bredesen Protocol.
A certified functional medicine doctor with an interest in holistic/integrative medicine, Dr. Broyles is transforming medical care in rural North Carolina. Addressing the underlying causes of disease rather than simply treating symptoms, Dr. Broyles uses a systems-oriented, holistic approach that engages both patient and practitioner in a therapeutic partnership. The result has been a palpable rise in health IQ and wellness in the community she serves.
“People are hungry for this kind of patient/physician collaborative care. They want to take charge of their well-being. They want to feel empowered. Too often, though, the insurance system in America limits choices for physicians and patients alike. Functional medicine represents a fundamental paradigm shift from symptom suppression to an integrative body/mind approach to optimal health,” said Dr. Broyles.
Hoping to help more people than her limited practice can accommodate, Dr. Broyles is reaching out to her community through the Cutting-Edge Health podcast and other platforms. At the end of each podcast, Dr. Broyles will answer your questions.
Having graduated from the Brody School of Medicine at East Carolina University and completed her three-year residency at the University of Tennessee in Knoxville, Dr. Broyles is currently a family practitioner in Saluda, North Carolina.
For the past several years, she served patients at urgent care and occupational medicine centers in South Carolina and Tennessee. Prior to this, she was medical director for the East Tennessee Spine and Nerve Center in Chattanooga and the Johnson City Tennessee Downtown Clinic. Dr. Broyles graduated from Brody school of medicine at East Carolina University in Greenville North Carolina and obtained her functional medicine certification from Functional Medicine university in Greer South Carolina.
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Thank you to our Cutting Edge Health supporters:
CZTL Methylene BlueGet a $10 discount by using this link: https://cztl.bz?ref=3OqY9 on an order of $70 or more OR use this discount code at checkout: jane10
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Cutting Edge Health podcast website: https://cuttingedgehealth.com/
Cutting Edge Health Social and YouTube:YouTube channel: youtube.com/@cuttingedgehealthpodcast
Instagram - https://instagram.com/cuttingedgehealthpodcastFacebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756
Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan, Maria, Louis, and Nicole on the Cutting Edge Health team!

Dr. Jojo Yonce -Hyperbaric Oxygen Treatments Reverse Aging Process in First Clinical Trial

According to recent research conducted by Tel Aviv University (TAU) and the Shamir Medical Center in Israel, hyperbaric oxygen treatments (HBOT) administered to healthy aging adults can stop the aging of blood cells and even reverse the aging process. Remarkably, the treatments cause the blood cells of the adults to become biologically younger as the therapy progresses.  The study indicates that HBOT may induce significant senolytic effects including increasing telomere length and clearance of senescent cells in the aging populations. If one can slow or reverse aging, then the onset of age-related diseases like Alzheimer’s, cancer and heart disease are slowed, too.
In hyperbaric oxygen therapy patients experience increased air pressure within either a hard-sided or soft-sided enclosed chamber, often coupled with breathing concentrated oxygen. The pressure is similar to the pressure you feel when you dive to the bottom of the deep end of the swimming pool, according to Dr. JoJo Yonce, a neurofeedback specialist, with clinics in North and South Carolina.
Dr. Yonce says HBOT can be used as a powerful therapy for those in the early stages of Alzheimer’s disease and other forms of cognitive decline, because it, among other factors, increases stem cell production in the brain.  Dr. Yonce, a neurofeedback specialist, says that for some people — but not all — the oxygen therapy can reverse decline in memory. HBOT also creates brain-derived neurotrophic factor (BDNF), a molecule that affects memory. In addition it triggers sirtuin reaction, which affects healthy aging.
Ordinarily, Dr. Yonce recommends 20 to 80 sessions of hyperbaric oxygen therapy to support those experiencing cognitive decline, but the number depends on each patient’s individual situation. Some might require more, he explains. Each session of about 75 minutes in duration usually costs just over $100.
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Dr. JoJo Yonce is board-certified in neurofeedback and is a mentor for the Biofeedback Certification International Alliance (BCIA) board certification process. He helps train other practitioners to become board certified in neurofeedback.
He has four clinics in the Greenville, SC and Asheville, NC, areas; partners with several other clinics in overseeing neurofeedback case management; and serves as a consultant to doctors and clinics to help them deliver top notch neurofeedback care and improve their clinical outcomes.
He was in the Honors College at the University of South Carolina and graduated magna cum laude from Sherman College of Chiropractic with a doctorate in Chiropractic in 1998. Over the past decade he has focused on advanced training in integrative brain health, qEEG Brain Mapping, neurofeedback and other leading edge brain health therapies.
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Thank you to our Cutting Edge Health supporters:
CZTL Methylene BlueGet a $10 discount by using this link: https://cztl.bz?ref=3OqY9 on an order of $70 or more OR use this discount code at checkout: jane10
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Instagram - https://instagram.com/cuttingedgehealthpodcastFacebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756
Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan, Maria, Louis, and Nicole on the Cutting Edge Health team!

Dr. Chadwick Prodromos - Reverse Aging with Stem Cells for the Heart and Brain

Stem cell therapy has become the newest player in the quest to slow the aging process.
“It’s a fantastic tool,” says Dr. Chadwick C. Prodromos, who heads an institute that offers stem cell injections and conducts extensive research into the role stem cells can play in treating a variety of medical conditions.
Stem cell infusions — which do not require surgery — have proven successful, according to Dr. Prodromos, in countering short-term memory loss, brain fog and fatigue. Those conditions “diminish substantially,” after the injections, he reports. Stem cells, however, have not proven effective in treating Alzheimer’s disease. “Maybe some day,” the orthopedic surgeon says, “but not right now.”
Because the U.S. Food and Drug Administration has not yet approved this form of stem cell therapy, it is not available in the United States. But Dr. Prodromos’s institute, which is based in Chicago, offers the treatment in a number of other countries, including Mexico, Argentina and Antigua.
The Prodromos Stem Cell Institute began by treating patients with neurological disorders like spinal cord injuries, strokes, and cerebral palsy, and got “people out of their wheelchairs,” Dr. Prodromos says. They then adapted the process for anti-aging “not just for people with serious problems, but for people who want to, I hate to use the word, but rejuvenate their heart or their brain.”
Dr. Prodromos says he uses adult rather than embryonic stem cells. The therapy thus does not raise ethical concerns once claimed by abortion foes over fetal stem cells.
Learn more about Dr. Prodromos's ideas and programs for prolonging life and the Prodromos Stem Cell Institute at https://www.thepsci.com/
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Dr. Chadwick C. Prodromos, director of the Prodromos Stem Cell Institute (PSCI), is an international leader in the use of stem cell and platelet rich plasma treatments. He received his bachelor’s degree with honors from Princeton University and his MD from the Johns Hopkins Medical School. He served his surgical internship at the University of Chicago, his orthopedic surgery residency at Rush University and his fellowship in orthopedics and sports medicine at the Harvard Medical School and Massachusetts General Hospital. He is board certified in orthopedic surgery and is editor of a major textbook for orthopedic surgeons on the ACL.
Dr.  Prodromos was an assistant professor of orthopedic surgery at Rush University for 27 years before leaving to focus on his foundation and stem cell work. He is also medical director of “The FOREM” (The Foundation for Regenerative Medicine), which supports ongoing prospective studies of the more than 4,000 biologic treatments he and his staff have performed. The continued follow-up, research and data collection distinguishes the PSCI from other clinics in the field.
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Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan, Maria, Louis, and Nicole on the Cutting Edge Health team!

Dr. Michael Roizen - You Are Your Own Genetic Engineer - Cutting Edge Health Audio Podcast

Dr. Michael Roizen, chief wellness officer emeritus of the Cleveland Clinic and author of nine best-selling books, has developed a concept, RealAge, that motivates people to take control of their lives in a way that will help them live longer and healthier.
“The most important thing for people to understand is they're a genetic engineer,” he maintains. The choices people make in how they live can determine how long they live. His RealAge program, which suggests that people at the age of 90 will soon be able to live like 40-year-olds, advocates taking steps to remain physically active, reduce stress and continue social engagement. All can prolong life span and assure greater health.
“When you do stress management or when you do physical activity, you change which of the genes are in or not in your cells,” Dr. Roizen says. Stressing a muscle, he explains, can send a protein to one’s brain that can fertilize the hippocampus and act as Miracle Grow for the brain. This, in turn, can reduce the likelihood of dementia and other forms of cognitive dysfunction.
Every person, he says, can reach their own “real age” by choosing their method of activity. ”If you don't like walking, you can do gardening, you can play with your kids, you can play ping pong,” Dr. Roizen says. “It's any activity. Do things you love that love you back.”
People can learn more of Dr. Roizen’s ideas and programs for prolonging life through his book, The Great Age Reboot, or visiting the app, Reboot Your Age (greatagereboot.com).
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Like many physicians now engaged in controlling the aging process, Dr. Michael Roizen entered the field from different medical specialties. He is board certified in both internal medicine and anesthesiology. He was running a step-down ICU at the University of California San Francisco Medical Center studying the outcome of patients who had undergone cardiovascular surgery. “It wasn't their cardiac history or their lung function or their liver function or kidney function or their brain function that determined outcome,” he discovered. “What determined the outcome was their age.” He then embarked on a new mission as a physician - motivating patients to take charge of the way they aged.
Dr. Roizen served as Cleveland Clinic’s first Chief Wellness Officer from 2007 to 2019. He now serves fifty percent time as the Cleveland Clinic’s Chief Wellness Officer Emeritus, and the other half as a Professor at the Learner College of Medicine of the Cleveland Clinic at Case Western Reserve University.
He is a recipient of an Emmy, an Elle, and the Paul Rogers Best Medical Communicator Award from the National Library of Medicine. He initiated and developed the RealAge concept to motivate behavior change.  He believes that soon 90 will be the new 40, and how one can prepare for it is described in his most recent book, The Great Age Reboot, and Reboot Your Age app.
Dr. Roizen is a Phi Beta Kappa graduate of Williams College and became a member of the American Osteopathic Association after graduating from UCSF School of Medicine. 
He has authored over 195 peer reviewed scientific publications, four New York Times #1 bestsellers, and nine overall bestsellers.  He and Dr. Mehmet Oz co-authored a daily column syndicated to over 100 newspapers that translates current scientific reports into actionable steps for lay audiences.
A recipient of The United Way of Cleveland Humanitarian of the Year Award, Dr. Roizen has won over 75 trophies in class A squash competition.  He practices what he preaches when it comes to enhancing his health and life expectancy, even working at a treadmill desk to help achieve his goal of walking at least 10,000 steps a day.
He and his wife, who is also a medical doctor, have two children: Jenny, a PhD organic chemist working for the US Energy Department, and Jeffrey, an MD/PhD faculty member in pediatric endocrinology at Children’s Hospital of Philadelphia.
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Cutting Edge Health podcast website: https://cuttingedgehealth.com/
Cutting Edge Health Social and YouTube:YouTube channel: youtube.com/@cuttingedgehealthpodcast
Instagram - https://instagram.com/cuttingedgehealthpodcastFacebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756
Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan, Maria, Louis, and Nicole on the Cutting Edge Health team!

Dr. Jeffrey Gladden - Can 100 really become the new 30? - Cutting Edge Health Audio Podcast

Dr. Jeffrey Gladden’s foremost ambition is to help people live well beyond 100 years. That goal also entails assuring that individuals who live to be 120 or 130 years keep active and in tiptop shape — both physically and mentally.
“Being in shape is being fast, agile, strong, quick, balanced, flexible with great cardiovascular endurance and good recovery,” he explains. “If you’re going to have that later in life, you’ve got to focus on all of those things.”His medical program, Gladden Longevity, is engaged in working to realize those ambitions.
“We currently have a research protocol that’s in play for people to participate in, where that’s literally what we’re going for,” he says. “What we’re really going for is making 100 the new 30.”
While his program has therapies and devices that he says can help people achieve those objectives (though they can be costly), individuals can take direct action themselves to conquer the aging process. Rather than acquiescing to the traditional idea that aging means slowing down and losing impact, they can reject that belief and keep moving positively forward. Good sleep and eating habits, and remaining physically active, can contribute to that upward arc.
“If you’re asking questions,” he says, “that’s growth. If you’re stuck with your answers, that’s decline, quite honestly. Having a growth mindset is critical.”
Dr. Gladden’s strategy involves four interlacing “circles” -  health, longevity, performance and life energy. He says people should approach these concepts exponentially rather than from a linear perspective.*****Dr. Jeffrey Gladden is the founder, medical director and CEO of Gladden Longevity, a Texas-based concierge medical program established to optimize individuals’ health and prolong their lives. Clients are given customized treatment plans configured to their own individual situations.
Dr. Gladden segued into his work in age management medicine, functional medicine and integrative medicine from his earlier career as a cardiologist — at least in part because he had witnessed his own healthy body and mind begin to slide downhill as he moved through middle age. d feel myself go over this cliff of depression.”He received a bachelor of science degree in chemistry from Wheaton College in 1976. He went on to earn a doctor of medicine degree from Temple University Medical School in 1982 and a degree in internal medicine from Case Western Reserve University of Medicine in 1985. From 1985 through 1988 Dr. Gladden was part of the Interventional Cardiology Fellowship Program at the University of Colorado.
Besides his work at Gladden Longevity, he has spent the past decade as board chair, CEO and chief medical officer for product development at Scientia Cardio Access, a medical start-up in Salt Lake City that develops therapies and devices for medical interventional specialists.
He also has been, for the past 27 years, the CEO and president of Advanced Heart Care, a preventive diagnostic and interventional  cardiology practice in Texas. 
Thank you to our Cutting Edge Health supporters:
CZTL Methylene BlueGet a $10 discount by using this link: https://cztl.bz?ref=3OqY9 on an order of $70 or more OR use this discount code at checkout: jane10
Renue by Science: 10% off NMNhttps://renuebyscience.com/product/pure-nmn-sublingual-powder-30-grams/Enter jane10 at checkout for 10% off.
Cutting Edge Health podcast website: https://cuttingedgehealth.com/
Cutting Edge Health Social and YouTube:YouTube channel: youtube.com/@cuttingedgehealthpodcast
Instagram - https://instagram.com/cuttingedgehealthpodcastFacebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756
Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.
Special thanks to Alan, Maria, Louis, and Nicole on the Cutting Edge Health team!